Fundamental Understanding of Brain Structure and Function

Understanding the intricate workings of the brain is a cornerstone of neuroscience. This research area employs a multidisciplinary approach, integrating molecular biology, cellular biology, and systems neuroscience to investigate the structure and function of synapses, neurons, and neuronal circuits.

The institute is actively engaged in investigating long-term potentiation (LTP) and long-term depression (LTD) in synapses using two-photon microscopy to visualize real-time synaptic changes during learning tasks. We utilize optogenetics to manipulate specific neuronal circuits involved in behaviors such as fear conditioning, elucidating their roles in complex behaviors. Additionally, we employ functional magnetic resonance imaging (fMRI) and electrophysiology to study brain region activity during cognitive tasks, establishing links between brain structure and behavior.