The Brain and Intelligence Lunch Seminar NO.34
On March 4, the 34th Brain and Intelligence Lunch Seminar was successfully held at The Hong Kong University of Science and Technology (Guangzhou). We extend our sincere gratitude to Light Innovation Technology Limited for their generous support of this event, which is founded by HKUST alumni and faculty.
We welcomed Dr. ZHAO Luwei, CTO of Light Innovation Technology Limited , for an insightful seminar titled " LiTone Light Sheet microscope and LiTScan Analysis Software " . The talk centered on the LiTone light sheet microscope series and its advances in volumetric fluorescence imaging.
Light sheet microscopy enables high-speed optical sectioning via planar illumination, offering low photobleaching and phototoxicity for live specimens. Its imaging performance fundamentally depends on light sheet properties—thickness and effective field of view. While conventional Gaussian light sheets often compromise between axial resolution and field size, Line Bessel Sheet (LBS) technology optimizes beam propagation to achieve thinner optical sectioning without sacrificing the imaging field, substantially improving 3D resolving power.
Paired with the intelligent analysis software LiTScan, the LiTone system supports high-precision 3D reconstruction across diverse biological samples—from real-time imaging of living cells and embryos to complete visualization of cleared large tissues, including whole mouse brains, hearts, and livers. The seminar presented representative applications in developmental biology and neuroscience, followed by discussions on data processing workflows and imaging strategy optimization.
At the conclusion of the seminar, Dr. Zhao—an HKUST alumnus—shared his entrepreneurial journey with fellow students, offering three reflections drawn from his own experience. First, he emphasized the importance of anchoring innovation in one's areas of strength and identifying the core competitive edge of a technology. Second, he noted that cutting-edge research must be coupled with a sustainable business model to translate lab discoveries into real-world impact. Finally, he encouraged young researchers to stay focused and resist the temptation of too many options, stressing that meaningful breakthroughs require sustained commitment. His sincere insights resonated deeply with the audience and added a meaningful dimension to the academic event.
The Brain and Intelligence Lunch Seminar aims to promote subject integration and in-depth exchanges in the fields of brain science and artificial intelligence and create a relaxed and open academic exchange atmosphere for teachers and students to jointly discuss the cutting-edge scientific trends of brain and intelligence. We look forward to more experts, scholars and young talents joining us to jointly promote the prosperity and development of frontier fields related to brain and intelligence.